It is simple if you truly believe in Quran. God is unambiguously telling us in Quran, He is the One Who originated the first process, and He is the ONE who initiated Mary conceiving Jesus via a different process, an easy process for Him.
[3:47]: She said, "My Lord, how will I have a child when no man has touched me?" He said, Thus - LIKE THIS - Allah creates what He wills. When He decrees a matter, He only says to it, 'Be,' and it is.
[3:59-60]: Indeed, the example of Jesus to Allah is like that of Adam. He created Him from dust; then He said to him, "Be," and he was. The truth is from your Lord, so DO NOT BE AMONG THE DOUBTERS.
[19:21]: He said, Like this/Thus - your Lord says, 'IT IS EASY FOR ME, and We will make him a sign to the people and a mercy from Us. And it is a matter [already] decreed.' "
And finally, this is how she conceived:
[66:12]: And [the example of] Mary, the daughter of 'Imran, who guarded her chastity, so We blew into it our spirit/energy/ruh, and she believed in the words of her Lord and His scriptures and was of the devoutly obedient.